If you are using USB 1.0 ports, upgrade to 2.0. If you have a Firewire port, try to use that instead of a USB port since Firewire is faster than USB right now.
Your PC slows down while the Defragmenter is running, so you might prefer to set it to run manually – turn off scheduling by unticking Run on a Schedule (recommended). Alternatively, pick a time when you’re away from your PC – your lunch hour may be good, so it doesn’t interfere with your work.
26. Disable all unnecessary services. Depending on configuration, you may want to disable File and Print, FTP, World Wide Web, Routing and Remote Access, IIS Admin Service, Telnet, Smart Card and Smart Card Helper, Terminal Services, Uninterruptible Power Supply. Also make sure you disable Add New URL, as this usually significantly slows down your system.
Type %APPDATA%\Microsoft\Windows\sendto into the Start > Run box or Address bar to open your personal sendto folder. Drag a program shortcut into here (hold down Ctrl as you drag to ensure it’s copied rather than moved) and you can open a file in that program simply by right-clicking on the file and choosing Send to > Program name. This is perfect if, for example, you have a number of different image-editing tools installed on your PC and you need to choose a different one to the default.
The Power settings in Windows 7 is not automatically set for maximum performance. By default the power plan in Windows 7 is set for a balanced performance with energy consumption on hardware. So you may not get the optimal performance from windows 7 if this is the case. So we need to change the power plan to High Performance Mode.
Do you use a lot of IM Messengers? If you do, consider downloading Trillian. AIM, MSN, and Yahoo Messenger all use up a LOT of memory. With Trillian, you can connect to all of them with just one messenger. And honestly, Trillian uses less memory then either AIM, MSN, or Yahoo. Imagine how much memory it takes to run all three at once. If you are doing that, just download Trillian.This will instantly increase your PC speed.
Click the User Account Control settings. Now just drag the pointer to never Notify and stretch it to extremely below. Now Click “OK” and Reboot your system. Though the feature has been added for security reasons in windows vista and windows 7, however regularly it keeps coming on and irritates most of the time.